Successful medical treatment of two patients with eosinophilic oesophagitis
Autor: | J.L. Morales, J.C. Ollero, M.J. Canals, J. Soler, J. C. De Agustin, Juan José Vázquez, N. Sanz, E. Alvarez |
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Rok vydání: | 2002 |
Předmět: |
Male
medicine.medical_specialty Diet therapy Gastroenterology Diagnosis Differential Esophagus Elimination diet Internal medicine Eosinophilia medicine Esophagitis Humans Prospective Studies Child Food Formulated Esophageal disease business.industry General Medicine medicine.disease Radiography Treatment Outcome Pediatrics Perinatology and Child Health Esophageal Stenosis Etiology Surgery Barium Sulfate medicine.symptom Differential diagnosis business Rare disease |
Zdroj: | Journal of Pediatric Surgery. 37:207-213 |
ISSN: | 0022-3468 |
DOI: | 10.1053/jpsu.2002.30256 |
Popis: | Background/Purpose: Significant oesophageal eosinophilia is associated with oesophagitis and gastroesophageal reflux (GER). Eosinophilic oesophagitis is a rare disease that causes thickening of the oesophageal wall, narrowing of the oesophageal lumen, and severe motor disturbance. Methods and Results: Two 12 yr-old patients with eosinophilic oesophagitis were studied prospectively. Clinical and investigation details are presented. Elemental formula was administered until complete remission of disease. Final outcome was assessed after 3 months on regular diet with exclusion of specific allergic components. Both patients responded to the dietary manipulation. Conclusions: Eosinophilic oesophagitis must be included in the differential diagnosis when dealing with oesophageal strictures of unknown or unclear aetiology. Elimination diet therapy plays a crucial role in ameliorating the course of the illness. Blood eosinophilia correlates with therapeutic response and with improvement of the disease. J Pediatr Surg 37:207-213. Copyright © 2002 by W.B. Saunders Company. |
Databáze: | OpenAIRE |
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