Successful medical treatment of two patients with eosinophilic oesophagitis

Autor: J.L. Morales, J.C. Ollero, M.J. Canals, J. Soler, J. C. De Agustin, Juan José Vázquez, N. Sanz, E. Alvarez
Rok vydání: 2002
Předmět:
Zdroj: Journal of Pediatric Surgery. 37:207-213
ISSN: 0022-3468
DOI: 10.1053/jpsu.2002.30256
Popis: Background/Purpose: Significant oesophageal eosinophilia is associated with oesophagitis and gastroesophageal reflux (GER). Eosinophilic oesophagitis is a rare disease that causes thickening of the oesophageal wall, narrowing of the oesophageal lumen, and severe motor disturbance. Methods and Results: Two 12 yr-old patients with eosinophilic oesophagitis were studied prospectively. Clinical and investigation details are presented. Elemental formula was administered until complete remission of disease. Final outcome was assessed after 3 months on regular diet with exclusion of specific allergic components. Both patients responded to the dietary manipulation. Conclusions: Eosinophilic oesophagitis must be included in the differential diagnosis when dealing with oesophageal strictures of unknown or unclear aetiology. Elimination diet therapy plays a crucial role in ameliorating the course of the illness. Blood eosinophilia correlates with therapeutic response and with improvement of the disease. J Pediatr Surg 37:207-213. Copyright © 2002 by W.B. Saunders Company.
Databáze: OpenAIRE