Prediction of the risk of hepatic failure in patients with portal vein invasion hepatoma after hepatic resection
| Autor: | Jyh-Cherng Yu, Ching Tzao, C.B. Hsieh, Yao-Chi Liu, T.W. Chen, C.Y. Yu, Heng-Cheng Chu, Huan-Fa Hsieh |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Carcinoma Hepatocellular Cirrhosis medicine.medical_treatment Gastroenterology chemistry.chemical_compound Postoperative Complications Risk Factors Internal medicine Hypertension Portal medicine Hepatectomy Humans Neoplasm Invasiveness In patient Risk factor Retrospective Studies Portal Vein business.industry Liver Neoplasms General Medicine Middle Aged medicine.disease Survival Rate Treatment Outcome Oncology chemistry Hepatocellular carcinoma Portal hypertension Female Surgery Radiology Liver function Neoplasm Recurrence Local Tomography X-Ray Computed business Indocyanine green Liver Failure Follow-Up Studies |
| Zdroj: | European Journal of Surgical Oncology (EJSO). 32:72-76 |
| ISSN: | 0748-7983 |
| DOI: | 10.1016/j.ejso.2005.09.003 |
| Popis: | Aim Hepatic failure can develop after curative hepatectomy in patients with a hepatocellular carcinoma (HCC) invading the portal vein, because of cirrhosis and excessive tissue loss. This study aimed to identify the risk factors for hepatic failure in such patients. Method Forty patients with an HCC invading the portal vein underwent curative hepatectomy from January 1995 to June 2003. Eight patients developed hepatic failure and died within 3 months. Possible risk factors for this were analysed using univariate and multivariate regression. These included the liver function index, surgical blood loss, tumour pattern, portal hypertension, estimated residual liver volume measured by computed tomography (ERLV CT ) and estimated residual liver volume using the indocyanine green (ICG) retention rate at 15min (ERLV ICG15 ). Results The ERLV CT smaller than the ERLV ICG15 and presence of portal hypertension were independent risk factors for post-hepatectomy hepatic failure. Conclusion Having portal vein invasion HCC with portal hypertension or an ERLV CT less than an ERLV ICG15 are significant predictors of post-hepatectomy hepatic failure. These factors are important considerations for patients with portal vein invasion HCC who could undergo curative hepatic resection. |
| Databáze: | OpenAIRE |
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