| Autor: |
William F, Foos, Catherine, Culp, Masumi, Asahi, Marena, Patronas |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
BMJ Case Reports. 15:e251066 |
| ISSN: |
1757-790X |
| DOI: |
10.1136/bcr-2022-251066 |
| Popis: |
Siponimod is a sphingosine-1-phosphate receptor modulator used as disease-modifying therapy for relapsing-remitting multiple sclerosis similar to Fingolimod which has been known to cause dose dependent fingolimod associated macular oedema (FAME). We report a case of delayed onset bilateral cystoid macular oedema in a patient with stable proliferative diabetic retinopathy who developed cystoid macular oedema in the setting of siponimod (Mayzent; Novartis Pharmaceuticals; Cambridge, Massachusetts, USA) use. As with FAME, cystoid macular oedema resolved in the patient’s eyes with drug cessation and adjunctive topical anti-inflammatory therapy. We highlight unique fluorescein angiographic findings within this class of drugs as well as the clinical challenge posed by comorbid diabetic and inflammatory ophthalmic pathology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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