Supplementary Figure 1A from Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

Autor: Joseph R. Testa, Siddharth Balachandran, Raja M. Flores, Suresh C. Jhanwar, Suresh Ramanathan, Eric A. Ross, Lauren A. Fox, Vladimir Khazak, Ting Zhang, Anna-Mariya Kukuyan, Craig W. Menges, Suraj Peri, Mitchell Cheung, Eleonora Sementino, Yinfei Tan
Rok vydání: 2023
DOI: 10.1158/1078-0432.22474002
Popis: Efficiency of infection of MM cell lines infected with a pWPI lentivirus that expresses GFP marker alone (pWPI, control) or with a pWPI lentivirus that expresses both GFP and either RIPK3 WT or RIPK3-KD. Representative images indicate efficiency of infection of RIPK3-negative MM cell lines M12 and MSTO211H. Photographs of GFP fluorescence and combined GFP plus brightfield were taken 24 h after the initiation of infection. Note that most cells infected with pWPI-RIPK3 WT were floating, dead cells.
Databáze: OpenAIRE