Protective Effects of Ambient Ozone on Incidence and Outcomes of Ischemic Stroke in Changzhou, China: A Time-Series Study
| Autor: | Shen Yao, Xingjuan Yao, Zhan Zhang, Huibin Dong, Minghui Ji, Yongquan Yu |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Risk medicine.medical_specialty China Health Toxicology and Mutagenesis Population lcsh:Medicine 030204 cardiovascular system & hematology generalized additive model Article Brain Ischemia Brain ischemia 03 medical and health sciences symbols.namesake 0302 clinical medicine Sex Factors Interquartile range Internal medicine Epidemiology ischemic stroke Medicine Humans Poisson regression Poisson Distribution education Stroke Aged time-series study education.field_of_study Air Pollutants business.industry Incidence (epidemiology) lcsh:R Public Health Environmental and Occupational Health Age Factors Middle Aged medicine.disease Confidence interval ozone symbols Female Seasons business 030217 neurology & neurosurgery |
| Zdroj: | International Journal of Environmental Research and Public Health International Journal of Environmental Research and Public Health, Vol 14, Iss 12, p 1610 (2017) International Journal of Environmental Research and Public Health; Volume 14; Issue 12; Pages: 1610 |
| ISSN: | 1660-4601 |
| Popis: | The potential beneficial effect of ozone (O3) on stroke had been identified experimentally and clinically, but these effects remain controversial in population-based studies. This study aimed to explore the epidemiological association between O3 and risk of ischemic stroke. Ischemic stroke related health data and air pollution data were obtained from the Center for Disease Control and Prevention and Environmental Monitoring Center in Changzhou between 2015 and 2016, respectively. The associations between the short-term exposure to O3 and daily ischemic stroke onsets and deaths were examined based on time-series generalized additive Poisson model. During the study period, daily ischemic stroke onsets and deaths decreased 0.340% (95% confidence interval (CI) −0.559% to −0.120%) and 0.697% (95% CI −1.103% to −0.290%) with an interquartile range (IQR) (41.1 µg/m3) increase in levels of ambient O3, respectively. The protective effects of O3 were more significant in men and elders and in the cool season than those in women and young people and in the warm season, respectively. The negative association was independent of PM2.5, PM10, SO2, NO2 or CO exposure. Acute O3 exposure was associated with decreased risk of ischemic stroke. These findings will help provide new insights into the relationship between ischemic stroke and ambient O3 concentrations. |
| Databáze: | OpenAIRE |
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