Chronic thromboembolic and pulmonary arterial hypertension share right ventricular and pulmonary artery CMR features
| Autor: | Rogério Souza, Nicolas Creuze, Denis Chemla, Marc Humbert, Carlos E. Rochitte, Susana Hoette, Gérald Simonneau |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.medical_specialty Cardiac Catheterization Heart Ventricles Hypertension Pulmonary Cardiac index Pulmonary Artery 03 medical and health sciences 0302 clinical medicine Afterload Cardiac magnetic resonance imaging medicine.artery Internal medicine medicine Humans 030212 general & internal medicine Heart Atria Pulmonary Wedge Pressure Vascular Diseases Lung Aged Body surface area lcsh:RC705-779 Pulmonary Arterial Hypertension medicine.diagnostic_test business.industry Central venous pressure Hemodynamics lcsh:Diseases of the respiratory system Middle Aged medicine.disease Pulmonary hypertension Magnetic Resonance Imaging medicine.anatomical_structure 030228 respiratory system Pulmonary artery Chronic Disease Cardiology Vascular resistance cardiovascular system Ventricular Function Right Female Vascular Resistance France business Pulmonary Embolism |
| Zdroj: | Pulmonology, Vol 25, Iss 4, Pp 248-251 (2019) |
| ISSN: | 2531-0437 |
| Popis: | Background: Cardiac magnetic resonance (CMR) imaging has gained importance in pulmonary hypertension (PH) and studies have demonstrated its use as a surrogate marker and in following treatment of these patients. The pathophysiology of PH differs between pulmonary arterial hypertension (PAH, group 1) and chronic thromboembolic PH (CTEPH, group 4). Objectives: The present study tested the hypothesis that PAH and CTEPH display different characteristics on CMR imaging. Methods: 46 patients were evaluated for pulmonary vascular disease in the French National Reference Center for PH (23 PAH and 23 CTEPH matched for age and gender). All patients had the right heart catheterization (RHC) and CMR imaging performed within 48 h. CMR imaging was performed on a 1.5 T scanner. Results: PAH and CTEPH had similar body surface area and similar invasive hemodynamics, including mean pulmonary arterial pressure, cardiac index, pulmonary vascular resistance and right atrial pressure. PAH and CTEPH had similar CMR data. Right ventricular (RV) morphology and function and pulmonary artery (PA) data were also similar. Conclusion: Age- and sex-matched PAH and CTEPH patients displayed similar values of the CMR indices of RV and PA morphology and function, suggesting that the RV-PA responses are similar in both groups, mostly related to the overall increase in after load. Keywords: Pulmonary hypertension, Cardiac magnetic resonance imaging, PAH, Chronic thromboembolic PH |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|