Regional left ventricular endocardial strains estimated from low-dose 4DCT: Comparison with cardiac magnetic resonance feature tracking

Autor: Ashish Manohar, Gabrielle M. Colvert, Juan E. Ortuño, Zhennong Chen, James Yang, Brendan T. Colvert, W. Patricia Bandettini, Marcus Y. Chen, María J. Ledesma‐Carbayo, Elliot R. McVeigh
Rok vydání: 2022
Předmět:
Zdroj: Medical physics. 49(9)
ISSN: 2473-4209
Popis: Estimates of regional left ventricular (LV) strains provide additional information to global function parameters such as ejection fraction (EF) and global longitudinal strain (GLS) and are more sensitive in detecting abnormal regional cardiac function. The accurate and reproducible assessment of regional cardiac function has implications in the management of various cardiac diseases such as heart failure, myocardial ischemia, and dyssynchrony.To develop a method that yields highly reproducible, high-resolution estimates of regional endocardial strains from 4DCT images.A method for estimating regional LV endocardial circumferentialThe 4DCT-derived regional strains correlated well with the CMR-derived regional strains (We have developed a novel method to estimate high-resolution regional LV endocardial circumferential and longitudinal strains from 4DCT images. Except for the definition of the mitral valve and LV outflow tract planes, the method is completely user independent, thus yielding highly reproducible estimates of endocardial strain. The 4DCT-derived strains correlated well with those estimated using a commercial CMR feature tracking software. The promising results reported in this study highlight the potential utility of 4DCT in the precise assessment of regional cardiac function for the management of cardiac disease.
Databáze: OpenAIRE