Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia
| Autor: | Devendra K. Agrawal, Oormila Kovilam, Daniel R. Kirkpatrick, Tyler A Smith |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
T-Lymphocytes
Immunology Article vitamin D deficiency Preeclampsia Pathogenesis Pre-Eclampsia Pregnancy medicine Vitamin D and neurology Humans Immunology and Allergy Vitamin D Endothelial dysfunction Health risk reproductive and urinary physiology Aspirin business.industry Anti-Inflammatory Agents Non-Steroidal Vitamins Vitamin D Deficiency medicine.disease female genital diseases and pregnancy complications Practice Guidelines as Topic embryonic structures Etiology Female business |
| Zdroj: | Expert Review of Clinical Immunology. 11:1055-1063 |
| ISSN: | 1744-8409 1744-666X |
| Popis: | Worldwide, preeclampsia is a significant health risk to both pregnant women and their unborn children. Despite scientific advances, the exact pathogenesis of preeclampsia is not yet fully understood. Meanwhile, the incidence of preeclampsia is expected to increase. A series of potential etiologies for preeclampsia have been identified, including endothelial dysfunction, immunological dysregulation, and trophoblastic invasion. In this literature review, we have critically reviewed existing literature regarding the research findings that link the role of vitamin D to the pathogenesis and immunoregulation of preeclampsia. The relationship of vitamin D with the suspected etiologies of preeclampsia underscores its clinical potential in the diagnosis and treatment of preeclampsia. |
| Databáze: | OpenAIRE |
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