Fatal meningococcal septicemia without meningeal signs, contribution of the peripheral smear in diagnosis: Report of a case
| Autor: | Jeenu Varghese, SJ Manasa, Deepti Mutreja, Nikhil Moorchung |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Microbiology (medical) Secondary Hemophagocytic Lymphohistiocytosis Pathology medicine.medical_specialty peripheral smear Multiple Organ Failure lcsh:QR1-502 Autopsy Neisseria meningitidis purpura fulminans lcsh:Microbiology Pathology and Forensic Medicine Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Sepsis Consumptive Coagulopathy hemic and lymphatic diseases medicine Coagulopathy lcsh:Pathology Humans 030212 general & internal medicine Skin postmortem business.industry General Medicine Disseminated Intravascular Coagulation medicine.disease Rash Meningococcal Infections Military Personnel medicine.anatomical_structure Meningococcemia without meningitis Shock (circulatory) Bone marrow medicine.symptom business Purpura fulminans lcsh:RB1-214 |
| Zdroj: | Indian Journal of Pathology and Microbiology, Vol 61, Iss 2, Pp 284-286 (2018) |
| ISSN: | 0377-4929 |
| Popis: | Acute meningococcemia is characterized by extensive purpurae consisting of both petechiae and ecchymoses. This condition can be rapidly fatal without treatment due to shock and severe consumptive coagulopathy. We report a case of fatal meningococcal septicemia in a military recruit who presented with fever and associated rapidly progressive purpuric rash (purpura fulminans) without any meningeal signs. Evaluation revealed evidence of disseminated intravascular coagulopathy and multiorgan failure. Diplococci were demonstrated in peripheral blood neutrophils and monocytes. On autopsy, extensive hemorrhages were found in both adrenals, lungs, liver, skin, and kidneys with secondary hemophagocytic lymphohistiocytosis in bone marrow. This report highlights useful information obtained from examination of peripheral blood smear in purpura fulminans. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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