Vascular Mineralization in the Monkey Brain
| Autor: | N. Matsunuma, K. Fujiwara, K. Ueda, M. Teranishi, T. Masegi, T. Yanai, K. Fukuda, J. Manabe, Naoaki Goto, M. Takaoka |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Pathology medicine.medical_specialty 040301 veterinary sciences chemistry.chemical_element Neurologic Signs 030204 cardiovascular system & hematology Calcium Biology Globus Pallidus Mineralization (biology) 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Calcinosis medicine Animals Von Kossa stain General Veterinary Magnesium Monkey Diseases 04 agricultural and veterinary sciences Anatomy medicine.disease Basophilic Macaca fascicularis Microscopy Electron Globus pallidus chemistry Female |
| Zdroj: | Veterinary Pathology. 31:546-552 |
| ISSN: | 1544-2217 0300-9858 |
| DOI: | 10.1177/030098589403100506 |
| Popis: | Mineralization of various degrees was found in the brains of 79 (59%) of 134 cynomolgus monkeys ( Macaca fascicularis). There was no age dependency in the incidence or severity, nor were there any abnormalities in growth, weight gain, or neurologic signs, although a slight sex difference was observed. The lesions, which were basophilic and intensely positive for periodic acid-Schiff or von Kossa stain, occurred in the vascular walls of the globus pallidus in two types: globoid bodies with prominent concentric lamellar structures in and around the arteriolar and venular wall (type A) and fine granules in the media of small or medium-sized arteries (type B). Electron microscopic examination revealed dense deposits in the degenerated media of small or medium-sized arteries or the thickened walls of the arterioles. X-ray microanalysis demonstrated the presence of calcium, phosphorus, iron, zine, magnesium, and aluminum. |
| Databáze: | OpenAIRE |
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