Increased serum adiponectin predicts improved coronary flow and clinical outcomes in patients with ST‐segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Autor: Siwen Liang, Xuhua Shen, Hongwei Li, Ruifeng Liu
Rok vydání: 2019
Předmět:
Male
0301 basic medicine
Microbiology (medical)
medicine.medical_specialty
medicine.medical_treatment
Clinical Biochemistry
acute myocardial infarction
Kaplan-Meier Estimate
myocardial blood flow
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Coronary Circulation
Internal medicine
medicine
Humans
Immunology and Allergy
ST segment
cardiovascular diseases
Myocardial infarction
Survival rate
Research Articles
Aged
adiponectin
Adiponectin
business.industry
Biochemistry (medical)
Public Health
Environmental and Occupational Health
Percutaneous coronary intervention
Hematology
Thrombolysis
Middle Aged
primary percutaneous coronary intervention
medicine.disease
Medical Laboratory Technology
Logistic Models
Treatment Outcome
030104 developmental biology
major adverse cardiac event
030220 oncology & carcinogenesis
Cardiology
ST Elevation Myocardial Infarction
Female
business
Biomarkers
hormones
hormone substitutes
and hormone antagonists
Mace
TIMI
Research Article
Zdroj: Journal of Clinical Laboratory Analysis
ISSN: 1098-2825
0887-8013
DOI: 10.1002/jcla.22864
Popis: Background Previous studies suggested that adiponectin (APN) could ameliorate ischemia/reperfusion injury and endothelial dysfunction in patients with acute myocardial infarction. However, the relationship between serum APN level and coronary flow after primary percutaneous coronary intervention (PPCI) in patients with ST‐segment elevation myocardial infarction (STEMI) is unclear. Methods A total of 144 patients with STEMI treated by PPCI were enrolled and divided into two groups based on the mean serum APN level on admission. The data on coronary angiograms and laboratory examinations were collected and compared between groups. The incidence of major adverse cardiac events (MACE) was evaluated in all enrolled patients. Results The prevalence of Thrombolysis In Myocardial Infarction (TIMI) flow grade
Databáze: OpenAIRE
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