Association of Weight-Adjusted Body Fat and Fat Distribution with Bone Mineral Density in Middle-Aged Chinese Adults: A Cross-Sectional Study
| Autor: | Ying Xu, Yu-ming Chen, Yan-hua Liu, Li-ping He, Ke Guan, Yi-xiang Su, Ya-bin Wen, Wenhua Ling |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Health Screening Anatomy and Physiology Non-Clinical Medicine Bone density Epidemiology Osteoporosis lcsh:Medicine Adipose tissue Absorptiometry Photon Bone Density Body composition Body Fat Distribution Whole Body Imaging lcsh:Science Bone mineral Lumbar Vertebrae Multidisciplinary Middle Aged Observational Studies Medicine Female Public Health Research Article musculoskeletal diseases China medicine.medical_specialty Clinical Research Design Bone and Mineral Metabolism Whole body imaging Abdominal Fat Body adiposity index Biology Rheumatology Classification of obesity Internal medicine medicine Humans Obesity Nutrition Aged Health Care Policy Hip lcsh:R Health Risk Analysis medicine.disease Cross-Sectional Studies Endocrinology lcsh:Q Physiological Processes |
| Zdroj: | PLoS ONE, Vol 8, Iss 5, p e63339 (2013) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0063339 |
| Popis: | BACKGROUND: Although it is well established that a higher body weight is protective against osteoporosis, the effects of body fat and fat distribution on bone mineral density (BMD) after adjustment for body weight remains uncertain. OBJECTIVE: To examine the relationship between body fat and fat distribution and BMD beyond its weight-bearing effect in middle-aged Chinese adults. METHOD: The study had a community-based cross-sectional design and involved 1,767 women and 698 men aged 50-75 years. The BMD of the lumbar spine, total hip, and whole body, and the fat mass (FM) and percentage fat mass (%FM) of the total body and segments of the body were measured by dual-energy X-ray absorptiometry. General information on the participants was collected using structured questionnaire interviews. RESULT: After adjusting for potential confounders, an analysis of covariance showed the weight-adjusted (WA-) total FM (or %FM) to be negatively associated with BMD in all of the studied sites (P |
| Databáze: | OpenAIRE |
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