Embracing the heterogeneity of natural viruses in mouse studies

Autor:	Jessica K. Fiege, Ryan A. Langlois
Rok vydání:	2022
Předmět:	Disease Models Animal Mice Virology Microbiota Viruses Animals Reproducibility of Results Symbiosis
Zdroj:	The Journal of general virology. 103(6)
ISSN:	1465-2099
Popis:	Animal models are a critical tool in modern biology. To increase reproducibility and to reduce confounding variables modern animal models exclude many microbes, including key natural commensals and pathogens. Here we discuss recent strategies to incorporate a natural microbiota to laboratory mouse models and the impacts the microbiota has on immune responses, with a focus on viruses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a73da9961a181069ce8b2872ea8b6e2 https://pubmed.ncbi.nlm.nih.gov/35737518 Zobrazit plný text záznamu