A new angiographic imaging platform reduces radiation exposure for patients with liver cancer treated with transarterial chemoembolization

Autor: Zhijun Wang, Rafael Duran, Jean Francois H. Geschwind, MingDe Lin, Ruediger E. Schernthaner, Julius Chapiro
Rok vydání: 2015
Předmět:
Adult
Male
medicine.medical_specialty
Radiation Dosage
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Image Processing
Computer-Assisted
medicine
Humans
Fluoroscopy
Therapeutic Chemoembolization
Radiology
Nuclear Medicine and imaging
Prospective Studies
Chemoembolization
Therapeutic
Prospective cohort study
Aged
Neuroradiology
Interventional radiology
Interventional
medicine.diagnostic_test
Therapeutic chemoembolization
business.industry
Liver Neoplasms
Ultrasound
Cone-beam computed tomography
Angiography
Digital Subtraction
General Medicine
Middle Aged
Radiation Exposure
medicine.disease
3. Good health
Radiation exposure
Radiology Nuclear Medicine and imaging
030220 oncology & carcinogenesis
Female
Radiology
Liver cancer
business
Nuclear medicine
Algorithms
Zdroj: European Radiology
ISSN: 1432-1084
0938-7994
Popis: Objectives To quantify the reduction of radiation liver cancer patients are exposed to during transarterial chemoembolization (TACE), while maintaining diagnostic image quality, using a new C-arm imaging platform. Methods In this prospective, HIPAA-compliant, IRB-approved, two-arm trial, 78 consecutive patients with primary or secondary liver cancer were treated with TACE on a C-arm imaging platform before and after an upgrade incorporating optimized acquisition parameters and advanced real-time image processing algorithms. Dose area product (DAP) and radiation time of each digital fluoroscopy (DF), digital subtraction angiography (DSA) and cone beam CT (CBCT) were recorded. DSA image quality was assessed by two blinded and independent readers on a four-rank scale. Results Both cohorts showed no significant differences with regard to patient characteristics and tumour burden. The new system resulted in a statistically significant reduction of cumulative DAP of 66 % compared to the old platform (median 132.9 vs. 395.8 Gy cm2). Individually, DAP of DF, DSA and CBCT decreased by 52 %, 79 % and 15 % (p
Databáze: OpenAIRE
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