Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure
| Autor: | Shuichi Yano, Toru Kadowaki, Masahiro Kimura, Kiryo Wakabayashi, Kanako Kobayashi, Toshikazu Ikeda |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
low-intensity noninvasive positive pressure ventilation
0301 basic medicine Pulmonary and Respiratory Medicine lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Exacerbation 03 medical and health sciences exacerbation 0302 clinical medicine medicine chronic respiratory failure Positive pressure ventilation lcsh:RC705-779 business.industry Clinical course lcsh:Diseases of the respiratory system Surgery Intensity (physics) 030104 developmental biology Adjustment 030228 respiratory system lcsh:RC666-701 Anesthesia Lower pressure Original Article Noninvasive ventilation noninvasive positive pressure ventilation business Cardiology and Cardiovascular Medicine Chronic respiratory failure |
| Zdroj: | Annals of Thoracic Medicine, Vol 11, Iss 2, Pp 141-145 (2016) Annals of Thoracic Medicine |
| ISSN: | 1817-1737 |
| DOI: | 10.4103/1817-1737.176881 |
| Popis: | BACKGROUND: For patients with chronic respiratory failure (CRF) who are treated with noninvasive positive pressure ventilation (NPPV), a little is known regarding the effects of low-intensity NPPV (LI-NPPV) on the clinical course of CRF and the frequency of adjustments in these patients. OBJECTIVES: This study investigated the effects of LI-NPPV on the clinical course of patients with CRF as compared with patients who were treated with conventional NPPV (C-NPPV) and determined how frequently NPPV was adjusted during therapy. METHODS: Clinical data from 21 patients who received long-term NPPV were retrospectively analyzed. Patients were categorized into two groups based on the level of initial pressure support (PS): C-NPPV group (PS ≥ 10 cm H2O) and LI-NPPV group (PS < 10 cm H2O). RESULTS: Patients in the LI-NPPV group had significantly more exacerbations of CRF (P < 0.05). There was no significant difference in the number of patients who required adjustments of NPPV settings between the two groups. There was no significant difference in PaCO2 levels 1 month after the start of NPPV between the two groups; however, PaCO2 levels were significantly lower after 1 year in the C-group (P < 0.001). Seventy-one percent of LI-NPPV patients and 43% of C-NPPV patients needed NPPV adjustments. CONCLUSIONS: Attention should be paid to CRF patients who are initially administered LI-NPPV; they should be carefully observed because they can develop more exacerbations of CRF than patients undergoing C-NPPV. If possible, higher initial PS should be administered to prevent CRF exacerbations. |
| Databáze: | OpenAIRE |
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