The ketogenic diet in refractory epilepsy: the experience of Children's Hospital of Pittsburgh
| Autor: | Patricia K. Crumrine, Anita N. Koehler, Catherine M. Foley, Neelam G. Katyal, Bill McGhee |
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| Rok vydání: | 2000 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Diet therapy medicine.medical_treatment 03 medical and health sciences Epilepsy 0302 clinical medicine Pharmacotherapy Refractory 030225 pediatrics medicine Dietary Carbohydrates Humans Treatment Failure Child Chemotherapy business.industry Infant Avitaminosis Electroencephalography Vitamins Ketones medicine.disease Lipid Metabolism Dietary Fats Surgery Anticonvulsant El Niño Child Preschool Pediatrics Perinatology and Child Health Female Dietary Proteins business Ketogenic diet Follow-Up Studies |
| Zdroj: | Clinical pediatrics. 39(3) |
| ISSN: | 0009-9228 |
| Popis: | The ketogenic diet appears to be effective in reducing seizure frequency in patients with epilepsy refractory to antiepileptic drug therapy. Reported seizure frequencies before and after the diet was initiated were obtained for 48 patients started on the ketogenic diet between December 1994 and January 1998 at Children's Hospital of Pittsburgh. The majority of patients (71%) were able to achieve?50% reduction in seizure activity. Of these, more than half (53%) had >90% reduction in seizures after 45 days of diet therapy. Complications included gastrointestinal complaints and infrequent lipid abnormalities. The ketogenic diet appears to be an effective method of treatment for children with epilepsy refractory to drug therapy. |
| Databáze: | OpenAIRE |
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