| Autor: |
Kenji Yokoi, Biana Godin, Mauro Ferrari, Yuki Saito, Jenolyn F. Alexander, Xuewu Liu, Fransisca Leonard, Tomonori Tanei |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22409004.v1 |
| Popis: |
Dynamic light scattering analysis of nAb-PTX dispersed in water. The mean diameter of the aggregates is 12.4nm ; Gross appearance of breast (4T1) and lung (3LL) liver metastasis following various therapies ; Histological evaluation (H&E) consequently revealed that the tumor diameters at microscopic level in breast (4T1 cells) or lung (3LL cells) liver metastases were significantly smaller in the mice treated with MSV-nAb-PTX as compared to other therapy groups ; Dose response curves of viability of 4T1, 3LL cells, and abdominal macrophages treated with nAb-PTX and MSV-nAb-PTX as determined by MTT and WST-1 assay ; MSV biodistribution in 4T1 primary tumor and liver in the mice pre-treated with/without clodronate liposomes was evaluated by ICP-AES analysis . |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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