Effects of persistent organic pollutants on the thyroid function of the European sea bass (Dicentrarchus labrax) from the Aegean sea, is it an endocrine disruption?

Autor: Ursula Siebert, Jean-Pierre Thomé, E. T. Koutrakis, Joseph Schnitzler, Krishna Das
Rok vydání: 2008
Předmět:
Thyroid hormones
Sea bass
Thyroid Gland
Aquaculture
Endocrine Disruptors
Oceanography
Endocrine diseases
Fish Diseases
Mediterranean sea
groupers and fairy basslets] [Serranidae [Sea basses]
Thyroid
Mediterranean Region
Ecology
Endocrine systems
food and beverages
Polychlorinated Biphenyls
Bioaccumulation
Pollution
Chlorine compounds
medicine.anatomical_structure
Endocrine disruptor
Dicentrarchus labrax [Bass]
Dicentrarchus
Thyroid function
geographic locations
endocrine system
Histology
Oceans and Seas
Zoology
Aquatic Science
Biology
DDT
Persistence
Polychlorinated biphenyls
Arsenic compounds
medicine
Animals
MED
Aegean
Muscle
Skeletal
Water pollution effects
Pollutant
Persistent organic pollutant
Morphometry
organic chemicals
biology.organism_classification
Hormones
Bass
Water Pollutants
Chemical
Zdroj: Marine Pollution Bulletin. 56:1755-1764
ISSN: 0025-326X
Popis: We evaluated the alterations of organochlorinated compounds such as polychlorobiphenyls (PCB), dichloro-diphenyl-dichloroethylene (DDE) and dichloro-diphenyl-trichloroethane (DDT) on the thyroid in wild and cultured sea bass (Dicentrarchus labrax) at environmental concentrations. These compounds influence the endocrine system of many fish species and are qualified as endocrine disruptors. The thyroid seems to be a target organ. Two alteration endpoints: the thyroid histology and the muscular thyroid hormone concentrations, were used simultaneously. High concentrations in PCBs and DDT were detected in muscles, supporting the idea that the Mediterranean fauna could be more polluted than the Atlantic fauna. The high abundance of DDE indicates a progressive degradation of remnant DDT load and the absence of new inputs in this area. Aquaculture sea bass shows a significant higher amount of pollutants on fresh weight basis (especially PCBs) in their muscles compared to the wild sea bass. Those differences may be related mainly to the contaminations of diet. Thyroid parameters vary between wild and aquaculture sea bass, wild sea bass were characterized by higher follicle diameters, epithelial cell heights and muscular T4 concentrations. A significant relationship between persistent organic pollutants (muscular PCBs and DDT concentration) and the different thyroid parameters (diameters of follicles, epithelial cell heights and muscular T4 levels) could be observed, which support the hypothesis that these compounds have an adverse impact on thyroid morphometry and function.
Databáze: OpenAIRE
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