Supplementary Figure 1 from PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer

Autor: Khashayarsha Khazaie, Philipp Beckhove, David J. Bentrem, Terrence A. Barrett, Hyunji Ryu, Goo Lee, Fu-Nien Tsai, Zongmin E. Chen, Nichole R. Blatner, Eric C. Cheon, Joshua E. Melson, Elias Gounaris, Ali Keshavarzian, Mohammad W. Khan
Rok vydání: 2023
Popis: PDF file - 153K, LY294002 attenuates mast cell mediated CD11b+ cell migration. Representative images of migration of CD11b cells in response to (A) Stempro +SCF (control), (B) LAD-2 CM (LAD-2 conditioned medium), (C) LAD-2 CM + 10 �M LY294002 (LAD-2 CM with 10 �M LY294002) and (D) CM obtained after pretreatment of LAD-2 cells with 10 �M LY294002. (E) Purity of CD11b+ cells obtained after using either biotinylated Rat ant-human CD11b or biotinylated Rat IgG2bK. Black arrows indicate migrated CD11b+ cells. Black scale bar = 20 �m.
Databáze: OpenAIRE