Long-term sensitization training primes Aplysia for further learning
| Autor: | Leonard J. Cleary, Marcy Wainwright, Evangelos G. Antzoulatos, John H. Byrne |
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| Rok vydání: | 2006 |
| Předmět: |
Time Factors
Long term sensitization Cognitive Neuroscience Stimulation Sensory system Functional Laterality Developmental psychology Cellular and Molecular Neuroscience Memory Aplysia medicine Animals Learning Neurons Afferent Sensitization Control treatment biology Extramural biology.organism_classification Neuropsychology and Physiological Psychology medicine.anatomical_structure Functional significance lipids (amino acids peptides and proteins) Psychology Neuroscience |
| Zdroj: | Learningmemory (Cold Spring Harbor, N.Y.). 13(4) |
| ISSN: | 1072-0502 |
| Popis: | Repetitive, unilateral stimulation of Aplysia induces long-term sensitization (LTS) of ipsilaterally elicited siphon-withdrawal responses. Whereas some morphological effects of training appear only on ipsilateral sensory neurons, others appear bilaterally. We tested the possibility that contralateral morphological modifications may have functional significance. Therefore, we examined whether LTS training primes subsequent sensitization. Twenty-four hours after LTS training the effects of brief shock treatment (BST) were examined. BST failed to sensitize animals that had previously received either 4-d control treatment or 4-d ipsilateral LTS training. In contrast, BST did sensitize animals that had previously received 4-d contralateral LTS training, suggesting the presence of a latent trace that primes the animal for further learning. |
| Databáze: | OpenAIRE |
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