Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests

Autor:	Kenneth Chu, Ray Wada, Suni Boraston, Annie Mak, Inna Sekirov, Jesse Kustra, Mel Krajden, Jonathan Laley, Rosemarie Blancaflor, Rohit Vijh, Muhammad Morshed, Althea S. Hayden, Lori Willis, Paul N. Levett, Min-Kuang Lee, Navdeep Chahil, Meghan McLennan, Fred Burgess, Erin Carruthers, Tamara Pidduck
Rok vydání:	2020
Předmět:	0301 basic medicine medicine.medical_specialty Point-of-care testing Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 030106 microbiology Gastroenterology Immunoglobulin G Serology Rapid Point of Care Test 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Finger prick biology business.industry Brief Report COVID-19 Venous blood medicine.disease Hemolysis AcademicSubjects/MED00290 Infectious Diseases Oncology Diagnostic Microbiology biology.protein Public Health Antibody business
Zdroj:	Open Forum Infectious Diseases
ISSN:	2328-8957
Popis:	A comparison of rapid point-of-care serology tests using finger prick and venous blood was done on 278 participants. In a laboratory setting, immunoglobulin G (IgG) sensitivity neared 100%; however, IgG sensitivity dramatically dropped (82%) in field testing. Possible factors include finger prick volume variability, hemolysis, cassette readability, and operator training.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a436f55aabc5541c91747c978d330b7 https://pubmed.ncbi.nlm.nih.gov/33723509 Zobrazit plný text záznamu