Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review
| Autor: | Abeer Al Bawab, Dima Khater, Walhan Alshaer, Mais M. Saleh, Hamdi Nsairat, Areej M. Jaber, Fadwa Odeh, Mohammad S. Mubarak |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
dermal and transdermal delivery
Aging Materials science Lipid nanocarriers Pharmaceutical Science Nanoparticle Nanotechnology 02 engineering and technology Dermatology 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Solid lipid nanoparticle Stratum corneum medicine Chemical Engineering (miscellaneous) QD1-999 Transdermal Skin care integumentary system Penetration (firestop) 021001 nanoscience & nanotechnology stratum corneum (SC) lipid nanocarriers (NLC) Chemistry medicine.anatomical_structure solid lipid nanoparticles (SLN) Surgery 0210 nano-technology |
| Zdroj: | Cosmetics, Vol 8, Iss 39, p 39 (2021) |
| ISSN: | 2079-9284 |
| Popis: | Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles as they not only facilitate penetration across skin but also avoid the drawbacks of conventional skin formulations. This review focuses on solid lipid nanoparticles (SLNs), nanostructured lipid nanocarriers (NLCs), and nanoemulsions (NEs) developed for topical and transdermal delivery of active compounds. A special emphasis in this review is placed on composition, preparation, modifications, structure and characterization, mechanism of penetration, and recent application of these nanoparticles. The presented data demonstrate the potential of these nanoparticles for dermal and transdermal delivery. |
| Databáze: | OpenAIRE |
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