Autor: |
Nobuyuki Takakura, Haruhiko Kishima, Kazuhiro Takara, Yasunori Fujimoto, Naoki Kagawa, Hideyuki Arita, Hiroyasu Kidoya, Fumitaka Muramatsu, Taku Wakabayashi, Tomohiro Iba, Yonehiro Kanemura, Hisamichi Naito, Yohei Tsukada, Daisuke Eino |
Rok vydání: |
2023 |
DOI: |
10.1158/0008-5472.22418390.v1 |
Popis: |
Supplementary Figure 1. Coverage of pericyte and the basal membrane by LPA. Expression of LPA4 in several tumors. Supplementary Figure 2. Survival of wild-type and LPA4-KO mice harboring LLC brain tumors treated with or without LPA in the presence or absence of 5-FU. Supplementary Figure 3. Junctional protein expressioon in vascular endothelial cells by LPA. Supplementary Figure 4. LPA induces ICAM-1 expression but doesn't alter the expression of an HEV marker protein on endothelial cells Supplementary Figure 5. Investigation of LPA mediated VCAM-1 expression in MS-1 cells by using several inhibitors. Supplementary Figure 6. PD-L1 expression in GL261 brain tumors and LLC subcutaneous tumors. HE staining of the brain after anti-PD-1 antibody and LPA treatment. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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