Anthelmintic efficacy of oxibendazole against gastrointestinal nematodes in swine

Autor: Rafael Paranhos de Mendonça, Daniela Oliveira Carneiro, Eliane Marucci Baccin, Márcia Richena Pirágine, Sara Menegatti Zoca, Luis Augusto Ferreira Rossa, Guilherme Cecílio Lima, Francismar Barbosa de Oliveira, Istanlei Soares Costa, Gabriel Nunes de Oliveira, Sabrina Nathália Louzada Nogueira, Thaís Rabelo dos Santos-Doni
Rok vydání: 2022
Předmět:
Zdroj: Revista Brasileira de Parasitologia Veterinária. 31
ISSN: 1984-2961
0103-846X
DOI: 10.1590/s1984-29612022009
Popis: In swine production, parasites, especially gastrointestinal helminths, generate considerable economic losses. Therefore, effective control measures, such as the use of the correct anthelmintics, are of paramount importance for maintaining profitability. The aim of the present study was to evaluate the efficacy of the anthelmintic oxibendazole, administered orally, in pigs (non-industrial) naturally infected with gastrointestinal nematodes. To that end, we selected 18 pigs naturally parasitized by gastrointestinal nematodes, as determined by examination of fecal samples (eggs per gram (EPG > 500) of feces), and divided them into two groups: treated (with a 10-day course of oxibendazole) and control (untreated). After the treatment period, the animals were euthanized. During necropsy, the helminths in the gastrointestinal tract were identified and quantified. The species identified were, in order of occurrence, Ascaris suum, Trichuris suis, Oesophagostomum dentatum, and Hyostrongylus rubidus. In Brazilian swine herds, traditional (non-industrial) production systems can favor the transmission of helminths. We found that treatment with oxibendazole was 100% effective against A. suum and H. rubidus, whereas it was 99.65% effective against O. dentatum and 99.20% effective against T. suis, significantly reducing helminth counts (P < 0.01 for all). We conclude that oxibendazole is effective in controlling the main helminths in swine.
Databáze: OpenAIRE
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