Efficacy of lifestyle interventions in patients with type 2 diabetes: A systematic review and meta-analysis
| Autor: | Jian-Hua Pan, Fang Chen, Dan Chen, Xiao-Li Huang, Tao-Tao Hu, Jing Chen |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
030209 endocrinology & metabolism Blood Pressure Disease Type 2 diabetes Motor Activity law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Patient Education as Topic law Risk Factors Internal medicine Diabetes mellitus Internal Medicine medicine Humans 030212 general & internal medicine Life Style Randomized Controlled Trials as Topic Glycated Hemoglobin business.industry Cholesterol HDL Cholesterol LDL medicine.disease Diet Blood pressure Diabetes Mellitus Type 2 Cardiovascular Diseases Meta-analysis Quality of Life Health education business Publication Bias Patient education |
| Zdroj: | European journal of internal medicine. 27 |
| ISSN: | 1879-0828 |
| Popis: | Background The current meta-analysis evaluated the outcomes of various lifestyle interventions, including diet modifications (DIET), physical activity (PA), and patient education (EDU) in reducing the risk of cardiovascular disease in patients with type 2 diabetes. Methods Randomized clinical trials comparing lifestyle intervention with “usual care” (control) in type 2 diabetes patients were hand-searched from medical databases by two independent reviewers using the terms “diabetes, cardiovascular risk, lifestyle, health education, dietary, exercise/physical activities, and behavior intervention”. Results Of the 235 studies identified, 17 were chosen for the meta-analysis. The average age of patients ranged from 50–67.3 years. Results reveal no significant difference between the groups, with respect to BMI, while PA and DIET yielded a greater reduction in HbA1c. Significant reduction in both systolic and diastolic pressures in the DIET group, and diastolic pressure in the PA group, was observed. HDL-c in the DIET group was significantly higher than the control group, while no change in LDL-c levels, was seen in all three intervention subtypes. There was no difference between the EDU vs. the control group in terms of HbA1c, blood pressure or HDL-c and LDL-c. Conclusion DIET intervention showed an improvement in HbA1c, systolic/diastolic blood pressure and HDL-c, with an exception of LDL-c and BMI, suggesting that nutritional intervention had a significant impact on the quality of life by reducing the cardiovascular risk in type 2 diabetes patients. |
| Databáze: | OpenAIRE |
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