Solid lipid nanoparticle-based calix[n]arenes and calix-resorcinarenes as building blocks: synthesis, formulation and characterization
| Autor: | Patrick Shahgaldian, Anthony W. Coleman, Imed Montasser, Florent Perret |
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| Rok vydání: | 2013 |
| Předmět: |
calix-resorcinarenes
Supramolecular chemistry Nanoparticle Nanotechnology Review Catalysis lcsh:Chemistry Inorganic Chemistry Drug Delivery Systems colloids Calixarene Solid lipid nanoparticle Humans Physical and Theoretical Chemistry lcsh:QH301-705.5 Molecular Biology Spectroscopy Active ingredient Drug Carriers calix[n]arenes nanocarriers Chemistry Organic Chemistry General Medicine Lipids Computer Science Applications body regions solid lipid nanoparticles lcsh:Biology (General) lcsh:QD1-999 Surface modification Nanoparticles encapsulation Nanocarriers Calixarenes Drug carrier supramolecular |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 21899-21942 (2013) |
| ISSN: | 1422-0067 |
| Popis: | Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. This paper presents an overview about the use of calix[n]arenes and calix-resorcinarenes in the formulation of SLNs. Because of their specific inclusion capability both in the intraparticle spaces and in the host cavities as well as their capacity for functionalization, these colloidal nanostructures represent excellent tools for the encapsulation of different active pharmaceutical ingredients (APIs) in the area of drug targeting, cosmetic additives, contrast agents, etc. Various synthetic routes to the supramolecular structures will be given. These various routes lead to the formulation of the corresponding SLNs. Characterization, properties, toxicological considerations as well as numerous corresponding experimental studies and analytical methods will be also exposed and discussed. |
| Databáze: | OpenAIRE |
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