Isoxsuprine hydrochloride in the horse: a review
| Autor: | C. G. Macallister, Ronald S. Erkert |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Lameness Animal Vasodilator Agents Blood viscosity Administration Oral Biological Availability Foot Diseases First pass effect Isoxsuprine Hydrochloride Oral administration Internal medicine Isoxsuprine Animals Medicine Horses Infusions Intravenous Osteitis Pharmacology Volume of distribution General Veterinary business.industry Tarsal Bones Laminitis Endocrinology Navicular syndrome Horse Diseases business medicine.drug |
| Zdroj: | Journal of Veterinary Pharmacology and Therapeutics. 25:81-87 |
| ISSN: | 1365-2885 0140-7783 |
| DOI: | 10.1046/j.1365-2885.2002.00386.x |
| Popis: | Isoxsuprine hydrochloride has been suggested for use in horses for treatment of navicular syndrome and laminitis. The drug has been shown to be a beta-adrenoreceptor antagonist with beta-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. In addition, the drug is capable of decreasing blood viscosity and platelet aggregation. Studies have shown i.v. isoxsuprine to have a plasma half-life of |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text