Encapsulation of anthocyanins from bilberries – Effects on bioavailability and intestinal accessibility in humans
| Autor: | Kathrin Jung, Ulrich Kulozik, Manuel Winter, Ralph Melcher, Karin Schwarz, Elke Richling, Dorothee Rogoll, Dolores Mueller |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
0301 basic medicine Whey protein Colon Biological Availability Vaccinium myrtillus Pilot Projects Analytical Chemistry Anthocyanins 03 medical and health sciences 0404 agricultural biotechnology Pharmacokinetics medicine Humans Citrus Pectin Food science Phloroglucinol aldehyde Intestinal Mucosa 030109 nutrition & dietetics Ileostomy Plant Extracts Chemistry digestive oral and skin physiology fungi food and beverages Bilberry extract Biological activity 04 agricultural and veterinary sciences General Medicine Middle Aged 040401 food science Healthy Volunteers Small intestine ddc Bioavailability Intestines carbohydrates (lipids) Whey Proteins medicine.anatomical_structure Pectins Female Food Science |
| Zdroj: | Food Chemistry. 248:217-224 |
| ISSN: | 0308-8146 |
| DOI: | 10.1016/j.foodchem.2017.12.058 |
| Popis: | Anthocyanins are flavonoids that have been suggested to provide beneficial health effects. The biological activity of anthocyanins is influenced by their pharmacokinetic properties, but anthocyanins are associated with limited bioavailability in humans. In the presented study, we investigated how the encapsulation of bilberry extract (BE), a source of anthocyanins, with either whey protein or citrus pectin influences the bioavailability and intestinal accessibility of anthocyanins in humans. We performed an intervention study that analyzed anthocyanins and their degradation products in the urine, plasma, and ileal effluent of healthy volunteers and ileostomists (subjects without an intact colon). We were able to show, that whey protein encapsulation modulated short-term bioavailability and that citrus pectin encapsulation increased intestinal accessibility during passage through the small intestine and modulated the formation of the degradation product phloroglucinol aldehyde (PGAL) in human plasma. |
| Databáze: | OpenAIRE |
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