Regions in theZ5 mating gene ofSchizophyllum commune involved in Y-Z binding and recognition

Autor:	Robert C. Ullrich, Wu J, Charles P. Novotny
Rok vydání:	1996
Předmět:	Genetics Mating type biology Genes Fungal Molecular Sequence Data Genes Homeobox Schizophyllum commune Locus (genetics) Schizophyllum biology.organism_classification Human genetics Homeobox Cloning Molecular Allele Molecular Biology Gene Alleles Sequence Deletion
Zdroj:	Molecular and General Genetics MGG. 252:739-745
ISSN:	1432-1874 0026-8925
DOI:	10.1007/bf02173981
Popis:	The A alpha mating locus of the woodrotting fungus Schizophyllum commune encodes two multiallelic genes, Y and Z, which regulate the A-pathway of development. The Y alleles contain a homeobox, suggesting that the Y proteins may be DNA-binding regulatory proteins. During mating, development is induced when Y from one mating partner interacts with Z from the other mating partner; self combinations of Y and Z are inactive. Two-hybrid analyses indicate that nonself combinations of Y and Z form heteromultimers and self combinations do not. To understand Y-Z binding and self-nonself recognition further we used mutagenesis and chimeras to identify regions in one allele of Z(Z5) that are involved in these processes. Here we report the results, which broadly define regions in Z5 that are essential for activity, Y-Z binding and Z5 allelic specificity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1fbd50c95c34c56c5a312f33882ebb https://doi.org/10.1007/bf02173981 Zobrazit plný text záznamu Full text from SpringerLink