Niche Cells Crosstalk In Neuroinflammation After Traumatic Brain Injury
| Autor: | Guanyi Wang, Enming Kang, Yibin Jia, Huijun Chen, Zishuo Guo, Xiaosheng He, Yuqing Ye |
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| Rok vydání: | 2021 |
| Předmět: |
Traumatic brain injury
Neurogenesis Review Disease Applied Microbiology and Biotechnology Extracellular vesicles Neural stem cell (NSC) 03 medical and health sciences High morbidity Neuroinflammation Brain Injuries Traumatic medicine Animals Humans Molecular Biology Ecology Evolution Behavior and Systematics 030304 developmental biology 0303 health sciences business.industry Brain Receptor Cross-Talk Cell Biology medicine.disease Nerve Regeneration Crosstalk (biology) Astrocytes Neuroinflammatory Diseases Microglia Neural regeneration business Neuroscience Developmental Biology |
| Zdroj: | International Journal of Biological Sciences |
| ISSN: | 1449-2288 |
| DOI: | 10.7150/ijbs.52169 |
| Popis: | Traumatic brain injury (TBI) is recognized as the disease with high morbidity and disability around world in spite of the work ongoing in neural protection. Due to heterogeneity among the patients, it's still hard to acquire satisfying achievements in clinic. Neuroinflammation, which exists since primary injury occurs, with elusive duality, appear to be of significance from recovery of injury to neurogenesis. In recent years, studied have revealed that communication in neurogenic niche is more than “cell to cell” communication, and study on NSCs represent it as central role in the progress of neural regeneration. Hence, the neuroinflammation-affecting crosstalk after TBI, and clarifying definitive role of NSCs in the course of regeneration is a promising subject for researchers, for its great potential in overcoming the frustrating status quo in clinic, promoting welfare of TBI patient. |
| Databáze: | OpenAIRE |
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