Staphylococcal toxic shock syndrome in a child with interleukin-17 inhibitor treatment for psoriasis
| Autor: | Raúl de Lucas Laguna, Rosario López López, Irene Amores Hernández, María de la Calle, Francisco Javier Aracil Santos, Mariano Silva Hernández, María Sánchez Martín, David Argumánez García |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Staphylococcus aureus Dermatology medicine.disease_cause 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Psoriasis Medicine Humans Abscess Child business.industry Interleukin-17 Toxic shock syndrome Staphylococcal Infections medicine.disease Rash Shock Septic 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Secukinumab Anuria Female Interleukin 17 medicine.symptom business |
| Zdroj: | Pediatric dermatologyREFERENCES. 37(5) |
| ISSN: | 1525-1470 |
| Popis: | A 6-year-old girl presented with fever, skin rash, anuria, and conjunctivitis that rapidly progressed to toxic shock syndrome. Following hospital discharge, she developed a staphylococcal abscess on the lower extremity. She had recently received the first two doses of the interleukin-17 (IL-17) inhibitor secukinumab for resistant plaque psoriasis. IL-17 is known to be essential in host defense against Staphylococcus aureus. To our knowledge, this is the first reported case of staphylococcal toxic shock syndrome (STSS) associated with an IL-17 inhibitor. |
| Databáze: | OpenAIRE |
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