Ultrasound-guided lumpectomy of nonpalpable breast cancer versus wire-guided resection: a randomized clinical trial
Autor: | A.J.A. Bremers, Sybren L. Meijer, Rob P. A. Boom, Frans D Rahusen, Hans F. J. Fabry, A H M Taets van Amerongen |
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Rok vydání: | 2002 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Breast Neoplasms Mastectomy Segmental law.invention Breast cancer Randomized controlled trial law medicine Mammography Humans Prospective Studies skin and connective tissue diseases Prospective cohort study Intraoperative Care medicine.diagnostic_test business.industry General surgery Lumpectomy Segmental Mastectomy medicine.disease Clinical trial Oncology Surgery Female Radiology Ultrasonography Mammary business Mastectomy |
Zdroj: | Annals of surgical oncology. 9(10) |
ISSN: | 1068-9265 |
Popis: | The wire-guided excision of nonpalpable breast cancer often results in tumor resections with inadequate margins. This prospective, randomized trial was undertaken to investigate whether intraoperative ultrasound (US) guidance enables a better margin clearance than the wire-guided technique in the breast-conserving treatment of nonpalpable breast cancers.Patients with a preoperative histological diagnosis of nonpalpable breast cancer that could be visualized both with US and mammography were included. Patients were randomized to undergo either a wire-guided or a US-guided excision. Adequate margins were defined asor=1 mm.Of 49 included patients, 23 were assigned to undergo wire-guided excision and 26 to undergo US-guided excision. One patient crossed over to US-guided excision after inadvertent wire displacement. Mean tumor diameter, specimen weight, and operating time were similar in both groups. The excision was adequate in 24 (89%) of 27 US-guided excisions and 12 (55%) of 22 wire-guide excisions (P =.007).US-guided excision seems to be superior to wire-guided excision with respect to margin clearance of mammographically detected and US-visible nonpalpable breast cancers. Patients do not have to undergo the unpleasant wire placement before surgery. |
Databáze: | OpenAIRE |
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