Morphology of the Lactotropes and Somatotropes of Man and Rhesus Monkeys
| Autor: | Jean Lambert Pasteels, Charles S. Nicoll, F.J. Ectors, Puttipongse Varavudhi, André Danguy, Philippe Gausset |
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| Rok vydání: | 1972 |
| Předmět: |
Male
Immunodiffusion medicine.medical_specialty Somatotropic cell Endocrinology Diabetes and Metabolism Clinical Biochemistry Radioimmunoassay Fluorescent Antibody Technique Biology Biochemistry Endocrinology Antibody Specificity Pregnancy Iodine Isotopes Lactation Internal medicine Methods medicine Animals Humans Antiserum Sheep Staining and Labeling Histocytochemistry Differential staining Postpartum Period Biochemistry (medical) Age Factors Haplorhini Electrophoresis Disc Prolactin Somatropin medicine.anatomical_structure Growth Hormone Pituitary Gland Female Rabbits Densitometry hormones hormone substitutes and hormone antagonists Postpartum period |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 34:959-967 |
| ISSN: | 1945-7197 0021-972X |
| Popis: | Histologic sections of the adenohypophyses of humans and rhesus monkeys were examined by differential staining methods and by an immunofluorescent procedure. In addition, the concentrations of prolactin and growth hormone (GH) in the adenohypophyses of the monkeys were estimated by disc electrophoresis and densitometry, and cell counts were performed on differentially-stained histologic sections. All of the glands examined had numerous somatotropes, which stained with orange G, and the same cells showed affinity for the fluorescent immune serum to hGH. The glands of the pregnant and postpartum women and of all the adult monkeys (lactating or nonlactating) contained prominent erythrosinophils (lactotropes) and these bound the fluorescent antiserum to ovine prolactin. The erythrosinophils did not react with the fluorescent antiserum to hGH and the orangeophils did not localize the fluorescent immune serum to ovine prolactin. The lactotropes were particularly numerous and hypertrophied in the lactating monke... |
| Databáze: | OpenAIRE |
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