Nitric Oxide Sensing in Plants Is Mediated by Proteolytic Control of Group VII ERF Transcription Factors
| Autor: | Prabhavathi Talloji, Jorge Vicente Conde, Mahsa Movahedi, Sophie Berckhan, George W. Bassel, David Alabadí, José León, Nurulhikma Md Isa, Jorge Lozano-Juste, Julie E. Gray, Simon P. Pearce, Nora Marín-de la Rosa, Michael J. Holdsworth, Daniel J. Gibbs, Guillermina M. Mendiondo, Alberto Coego, Daniel F. A. Tomé, Jim Beynon, Andreas Bachmair, Cristina Sousa Correia, Frederica L. Theodoulou, Bulut Hamali |
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| Rok vydání: | 2014 |
| Předmět: |
Arabidopsis thaliana
Proteolysis Germination Biology In Nitric Oxide Article Nitric oxide chemistry.chemical_compound Abscisic acid Ethylene QH301 Gene Expression Regulation Plant medicine Dormancy End rule pathway Transcription factor Molecular Biology Regulation of gene expression medicine.diagnostic_test Arabidopsis Proteins fungi food and beverages Element binding protein Cell Biology Seed germination Cell biology QR Oxygen Crosstalk (biology) Induced stomatal closure Basic-Leucine Zipper Transcription Factors chemistry Biochemistry Plant Stomata Signal transduction Factor CAPF1 Abscisic Acid Signal Transduction Transcription Factors |
| Zdroj: | Molecular Cell RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia instname |
| ISSN: | 1097-2765 |
| DOI: | 10.1016/j.molcel.2013.12.020 |
| Popis: | Summary Nitric oxide (NO) is an important signaling compound in prokaryotes and eukaryotes. In plants, NO regulates critical developmental transitions and stress responses. Here, we identify a mechanism for NO sensing that coordinates responses throughout development based on targeted degradation of plant-specific transcriptional regulators, the group VII ethylene response factors (ERFs). We show that the N-end rule pathway of targeted proteolysis targets these proteins for destruction in the presence of NO, and we establish them as critical regulators of diverse NO-regulated processes, including seed germination, stomatal closure, and hypocotyl elongation. Furthermore, we define the molecular mechanism for NO control of germination and crosstalk with abscisic acid (ABA) signaling through ERF-regulated expression of ABSCISIC ACID INSENSITIVE5 (ABI5). Our work demonstrates how NO sensing is integrated across multiple physiological processes by direct modulation of transcription factor stability and identifies group VII ERFs as central hubs for the perception of gaseous signals in plants. Graphical Abstract Highlights • We elucidate a general molecular mechanism for nitric oxide sensing in plants • Group VII ERFs act as nitric oxide sensors via the N-end rule pathway • Group VII ERFs are shown to mediate crosstalk between nitric oxide and abscisic acid • The N-end rule regulates nitric oxide homeostasis through group VII ERFs Gibbs et al. report that NO-dependent degradation of group VII ERF transcription factors by the N-end rule pathway mediates NO sensing and signal transduction, identifying these transcription factors as central hubs for the perception of gaseous signals in plants. |
| Databáze: | OpenAIRE |
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