Three cases of giant pilomatrixoma – considerations for diagnosis and treatment of giant skin tumours with abundant inner calcification present on the upper body
| Autor: | Yuko Higuma, Makoto Yamauchi, Kanae Ikeda, Satoshi Urushidate, Takatoshi Yotsuyanagi, Tamotsu Saito |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Skin Neoplasms Hypercalcaemia Skin tumours Biopsy Humans Medicine Basal cell carcinoma Aged medicine.diagnostic_test Upper body business.industry Calcinosis Pilomatrixoma medicine.disease Surgery Head and Neck Neoplasms Hypercalcemia Female Hair Diseases business Calcification |
| Zdroj: | Journal of Plastic, Reconstructive & Aesthetic Surgery. 63:e519-e524 |
| ISSN: | 1748-6815 |
| DOI: | 10.1016/j.bjps.2009.12.006 |
| Popis: | Summary Background Pilomatrixoma frequently occurs as a solitary, small tumour on the face or upper extremities of people younger than 20 years. Methods We report three cases of giant pilomatrixoma. In all these cases, outward appearances and imaging investigations suggested malignant tumours. Preoperative biopsies suggested that case 1 was a basal cell carcinoma, but cases 2 and 3 had no malignant features on biopsy. Two of the cases experienced rare complications – hypercalcaemia caused by parathyroid-related protein (PTHrP) production and multiple occurrences. Results All three tumours were removed with a 1–3-cm margin. The postoperative histopathologies showed pilomatrixoma in all three cases. Conclusions Rarely, pilomatrixoma develops to a giant size with various atypical outward appearances consistent with a malignant tumour. Preoperative clinical appearances frequently lead to misdiagnosis, and preoperative examinations are unreliable. Therefore, when a giant tumour with abundant inner calcification is present in a young patient, the possibility of a pilomatrixoma should be considered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect