The Alzheimer Myth and Biomarker Research in Dementia
| Autor: | Piet Eikelenboom, Rudi G. J. Westendorp, Willem A. van Gool, Ben Schmand, Edo Richard |
|---|---|
| Přispěvatelé: | Klinische Psychologie (Psychologie, FMG), Faculteit der Geneeskunde, Psychiatry, EMGO - Mental health, Neurology, Amsterdam Neuroscience, Amsterdam Movement Sciences |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Gerontology
Aging medicine.medical_specialty Younger age Plaque Amyloid Disease cerebrospinal fluid Age Older patients prevention Alzheimer Disease medicine Humans Dementia magnetic resonance imaging Senile plaques Psychiatry old-age dementia Aged neuroimaging General Neuroscience biomarkers Neurofibrillary Tangles General Medicine medicine.disease Psychiatry and Mental health Clinical Psychology Biomarker (medicine) Geriatrics and Gerontology Alzheimer's disease Psychology Dementia research |
| Zdroj: | Journal of Alzheimer's Disease, 31(supplement 3), S203-s209. IOS Press Richard, E, Schmand, B, Eikelenboom, P, Westendorp, R G & van Gool, W A 2012, ' The Alzheimer myth and biomarker research in dementia ', Journal of Alzheimer's Disease, vol. 31, pp. S203-S209 . https://doi.org/10.3233/JAD-2012-112216 Journal of Alzheimer's Disease, 31, S203-S209 Journal of Alzheimer's Disease, 31, S203-S209. IOS Press Journal of Alzheimer s disease, 31(3), S203-S209. IOS Press |
| ISSN: | 1387-2877 |
| DOI: | 10.3233/jad-2012-112216 |
| Popis: | The focus of most of the research on Alzheimer's disease in the last decades has been on senile plaques and neurofibrillary tangles. The vast majority of patients with Alzheimer's disease are over 75 years of age, whereas most of the research focuses on younger subjects. To consider old-age dementia as a homogenous well-defined condition ignores the complexity of this condition and limits the development of new diagnostic methods, preventive strategies, or treatment strategies that could be widely applicable in daily practice in the majority of the older patients. The current research on biomarkers focuses on correlates of plaques and tangles, which are poor markers in older dementia subjects. Acknowledging that dementia in old age is an essentially different condition from dementia at relatively younger age is needed and should lead to new approaches in dementia research. |
| Databáze: | OpenAIRE |
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