The clinical characteristic of eight patients of COVID‐19 with positive RT‐PCR test after discharge

Autor: Jian Liu, Hong Cao, Wenhui Liao, Lei Ruan
Rok vydání: 2020
Předmět:
Male
discharge standard
severe acute respiratory syndrome coronavirus‐2
Virus diseases
Procalcitonin
COVID-19 Testing
0302 clinical medicine
Medicine
030212 general & internal medicine
Research Articles
Medical record
Middle Aged
After discharge
Normal white blood cell count
Patient Discharge
Infectious Diseases
Real-time polymerase chain reaction
Carrier State
Female
030211 gastroenterology & hepatology
Research Article
Adult
China
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Real-Time Polymerase Chain Reaction
Antiviral Agents
Patient Readmission
03 medical and health sciences
positive RT‐PCR
Virology
Internal medicine
Humans
Pandemics
Aged
Retrospective Studies
Interleukin-6
SARS-CoV-2
readmission
business.industry
COVID-19
Blood Cell Count
COVID-19 Drug Treatment
corona virus disease 2019
Tomography
X-Ray Computed
business
Biomarkers
Zdroj: Journal of Medical Virology
ISSN: 1096-9071
0146-6615
DOI: 10.1002/jmv.26017
Popis: Corona virus disease 2019 (COVID‐19) was caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2). The phenomenon of positive real time reverse transcription polymerase chain reaction (RT‐PCR) result of SARS‐CoV‐2 in recovered patients had occurred and the research about these patients was rare. In our study, we did a retrospective review of medical records from COVID‐19 patients admitted to one ward of Tongji Hospital of Hua Zhong University of Science and Technology from 10 February to 13 April 2020. From 10 February to 13 April 2020, there were 108 patients of COVID‐19 admitted in the one ward of Tongji Hospital. Among them, eight cases were readmission patients because the RT‐PCR result of SARS‐CoV‐2 was positive again after discharge. On the second admission, they had no symptoms and their chest computed tomography was almost normal. Data from laboratory tests of the readmission patients showed that all eight patients had normal white blood cell count, lymphocyte count. The inflammatory factors like procalcitonin and interleukin 6 were normal. After treatment, two patients met the standard and were discharged. The other six patients were still in the hospital because their RT‐PCR of SARS‐CoV‐2 did not get three consecutive negative results and the course of two patients had persisted more than 90 days. We still needed to be alert that these patients could infect other people as a source of infection, and we also needed to be alert that these patients become chronic virus carriers. It also aroused our concern about the discharge standard of COVID‐19.
Highlights From 10 February to 13 April 2020, there were 108 patients of COVID‐19 admitted in the one ward of Tongji Hospital.Among them, eight cases were readmission patients because the RT‐PCR result of Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐COV‐2) was positive again after discharge.The course of two patients had persisted more than 90 days.We still needed to be alert that these patients become chronic virus carriers.It also aroused our concern about the discharge standard of COVID‐19.
Databáze: OpenAIRE
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