First-in-human robotic supermicrosurgery using a dedicated microsurgical robot for treating breast cancer-related lymphedema: a randomized pilot trial
| Autor: | Tom J M, van Mulken, Rutger M, Schols, Andrea M J, Scharmga, Bjorn, Winkens, Raimondo, Cau, Ferry B F, Schoenmakers, Shan S, Qiu, René R W J, van der Hulst, Maud E P, Rijkx |
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| Přispěvatelé: | RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: MA Plastische Chirurgie (9), MUMC+: MA AIOS Plastische Chirurgie (9), RS: NUTRIM - R2 - Liver and digestive health, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, Interne Geneeskunde, FHML Methodologie & Statistiek, RS: CAPHRI - R6 - Promoting Health & Personalised Care, MUMC+: MA Plastische Chirurgie (3), Plastische Chirurgie (PLC) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Microsurgery
Robot assistance Breast Neoplasms/surgery General Physics and Astronomy Pilot Projects 030230 surgery 0302 clinical medicine Robotic Surgical Procedures Medicine Surgical/methods Lymphedema/complications Prospective Studies Lymphedema lcsh:Science Prospective cohort study Netherlands Multidisciplinary Pilot trial Anastomosis Surgical First in human Robotics Middle Aged 030220 oncology & carcinogenesis Female Breast Cancer Related Lymphedema Quality of life medicine.medical_specialty FEASIBILITY Anastomosis Science Breast Cancer Lymphedema Breast Neoplasms General Biochemistry Genetics and Molecular Biology Article 03 medical and health sciences LYMPHATICOVENULAR ANASTOMOSIS Humans Reconstructive Surgical Procedures MICROVASCULAR ANASTOMOSIS Aged Anastomosis Surgical/methods business.industry technology industry and agriculture General Chemistry Plastic Surgery Procedures Translational research Lymphatic flow medicine.disease EFFICACY Surgery Microsurgery/methods body regions lcsh:Q business Robotic Surgical Procedures/instrumentation PERFORM |
| Zdroj: | Nature Communications Nature Communications, 11(1):757. Nature Publishing Group Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020) |
| ISSN: | 2041-1723 |
| Popis: | Advancements in reconstructive microsurgery have evolved into supermicrosurgery; connecting vessels with diameter between 0.3 and 0.8 mm for reconstruction of lymphatic flow and vascularized tissue transplantation. Supermicrosurgery is limited by the precision and dexterity of the surgeon’s hands. Robot assistance can help overcome these human limitations, thereby enabling a breakthrough in supermicrosurgery. We report the first-in-human study of robot-assisted supermicrosurgery using a dedicated microsurgical robotic platform. A prospective randomized pilot study is conducted comparing robot-assisted and manual supermicrosurgical lymphatico-venous anastomosis (LVA) in treating breast cancer-related lymphedema. We evaluate patient outcome at 1 and 3 months post surgery, duration of the surgery, and quality of the anastomosis. At 3 months, patient outcome improves. Furthermore, a steep decline in duration of time required to complete the anastomosis is observed in the robot-assisted group (33–16 min). Here, we report the feasibility of robot-assisted supermicrosurgical anastomosis in LVA, indicating promising results for the future of reconstructive supermicrosurgery. Reconstructive microsurgery is limited by the precision that human hands can achieve. Here, the authors demonstrate in a randomized clinical pilot trial the feasibility of robot-assisted supermicrosurgery using a dedicated microsurgical robot for the completion of lymphatico-venous anastomosis in the treatment of breast cancer-related lymphedema |
| Databáze: | OpenAIRE |
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