Developments in Antiviral Drug Design, Discovery and Development in 2004
| Autor: | Nicholas A. Meanwell, Mark Krystal, David J. Carini, Sing-Yuen Sit, John F. Kadow, Tao Wang, Kap-Sun Yeung, Stanley D'andrea, Michael A. Walker, B. N. Naidu, Paul Michael Scola, Alicia Regueiro-Ren, Makonen Belema |
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| Rok vydání: | 2005 |
| Předmět: |
Microbiology (medical)
Human cytomegalovirus Anti-HIV Agents medicine.drug_class viruses Molecular Sequence Data Drug Evaluation Preclinical medicine.disease_cause Antiviral Agents Virus Human metapneumovirus Hepatitis Viruses medicine Animals Humans Protease Inhibitors Amino Acid Sequence HIV Integrase Inhibitors Herpesviridae Nucleic Acid Synthesis Inhibitors Pharmacology Clinical Trials as Topic Ebola virus Molecular Structure biology business.industry Varicella zoster virus virus diseases Nucleosides Hepatitis C Hepatitis B Orthomyxoviridae medicine.disease biology.organism_classification Virology Severe acute respiratory syndrome-related coronavirus Drug Design HIV-2 HIV-1 Reverse Transcriptase Inhibitors Molecular Medicine Antiviral drug business |
| Zdroj: | Current Drug Target -Infectious Disorders. 5:307-400 |
| ISSN: | 1568-0053 |
| DOI: | 10.2174/156800505774912893 |
| Popis: | This article summarizes key aspects of progress made during 2004 toward the design, discovery and development of antiviral agents for clinical use. Important developments in the identification, characterization and clinical utility of inhibitors of human immunodeficiency virus; the hepatitis viruses, hepatitis B, hepatitis C; the herpes family of viruses, herpes simplex viruses 1 and 2, varicella zoster virus, Epstein-Barr virus and human cytomegalovirus; the respiratory viruses, influenza, respiratory syncytial virus, human metapneumovirus, picornaviruses, measles and the severe acute respiratory syndrome coronavirus; human papilloma virus; rotavirus; Ebola virus and West Nile virus, are reviewed. |
| Databáze: | OpenAIRE |
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