Comparison of Skin Antiseptic Agents and the Role of 0.01% Hypochlorous Acid
| Autor: | James H Lee, Apostolos G Anagnostopoulos, Nicole J. Topilow, Patrice J. Persad, Michael C. Lee, Wendy W. Lee, Ann Q. Tran, Andrew J. Rong |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Hypochlorous acid medicine.drug_class 030230 surgery Gastroenterology 2-Propanol 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Antiseptic Staphylococcus epidermidis Internal medicine Chlorhexidine gluconate medicine Humans 0601 history and archaeology Prospective Studies Povidone-Iodine Skin biology business.industry Chlorhexidine 06 humanities and the arts General Medicine biology.organism_classification Staphylococcus capitis Hypochlorous Acid Facial skin 060105 history of science technology & medicine chemistry Anti-Infective Agents Local Surgery Dermatologic Agents business |
| Zdroj: | Aesthetic surgery journal. 41(10) |
| ISSN: | 1527-330X |
| Popis: | Background Hypochlorous acid (HA) has both anti-microbial and wound-healing properties with a growing role for utilization in pre-procedural care on the face. Objectives The authors sought to compare the antiseptic property of 0.01% HA solution, 5% povidone iodine (PI), 4% chlorhexidine gluconate (CHG), and 70% isopropyl alcohol (IPA) antiseptic on facial skin. Methods This was a prospective single-center clinical trial. Results A total of 21 participants were recruited. Bacterial growth was seen in CHG (10%), IPA (71%), PI (81%), and HA (95%) of specimens (P Conclusions CHG reduced the bacterial growth compared with HA, PI, and IPA. However, HA, PI, and IPA had insignificant differences in bactericidal effects. Our study provides a supporting role of HA to be considered as an antiseptic. Level of Evidence: 2 |
| Databáze: | OpenAIRE |
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