Viral suppression among middle-aged and aging MSM living with HIV: Partnership type and quality

Autor: Vaibhav Penukonda, Sabina A. Haberlen, Timothy Utz, Andre L. Brown, Steven Meanley, Michael Plankey, James E. Egan, Deanna Ware, Steven Shoptaw, Mark Brennan-Ing, Linda A. Teplin, M. Reuel Friedman, Nicholas S. Perry
Přispěvatelé: Bavinton, Benjamin R
Rok vydání: 2021
Předmět:
RNA viruses
Male
Aging
Physiology
Emotions
Multicenter AIDS Cohort Study
Human immunodeficiency virus (HIV)
Social Sciences
HIV Infections
medicine.disease_cause
Pathology and Laboratory Medicine
Men who have sex with men
Cohort Studies
Sexual and Gender Minorities
Immunodeficiency Viruses
Sociology
Medicine and Health Sciences
Medicine
Ethnicities
Psychology
Viral suppression
Hispanic People
Multidisciplinary
Schools
Homosexuality
Viral Load
Middle Aged
Sexual Partners
Infectious Diseases
Medical Microbiology
General partnership
Viral Pathogens
Viruses
symbols
HIV/AIDS
Pathogens
Infection
Viral load
Research Article
Adult
General Science & Technology
Science
Sexual Behavior
Clinical Trials and Supportive Activities
Men WHO Have Sex with Men
Microbiology
Education
symbols.namesake
Negatively associated
Clinical Research
Virology
Retroviruses
Mental Health and Psychiatry
Behavioral and Social Science
Humans
Poisson regression
Homosexuality
Male
Microbial Pathogens
Aged
business.industry
Lentivirus
Organisms
Biology and Life Sciences
HIV
People and Places
Quality of Life
Population Groupings
business
Physiological Processes
Organism Development
Viral Transmission and Infection
Demography
Sexuality Groupings
Developmental Biology
Zdroj: PloS one, vol 16, iss 10
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258032 (2021)
Popis: Functional support—the availability of material aid, emotional support, or companionship—promotes general well-being. For men who have sex with men (MSM) living with HIV, having a person who supports you associates with viral suppression. This study examines the association between supportive partnerships and HIV viral suppression among middle-aged and aging MSM living with HIV. A total of 423 middle-aged and aging MSM (mean age, 58.2 years) from the Multicenter AIDS Cohort Study provided self-reported data about their partnerships. Separate Poisson regression models assessed how partnership type, support, strain, and duration from April 2017 were associated with repeated viral load measurements up to April 2019. Of the follow-up visits (N = 1289), 90.0% of participants were virally suppressed. Most participants reported being non-Hispanic White (61.0%) and college-educated (83.4%). Participants were asked about their primary partnerships (i.e., “someone they are committed to above anyone else”) and secondary partnerships (i.e., those who can also be intimate or supportive but not necessarily romantic or sexual). The participants reported: no partnerships (45.2%), only primary partnerships (31.0%), only secondary partnerships (11.1%), or both primary and secondary partnerships (12.8%). Primary and secondary partnerships had mean (SD) durations of 15.9 (11.3) and 25.2 (16.5) years, respectively. Participants reporting both primary and secondary partnerships (compared with no partnership) showed significantly higher odds of being virally suppressed (adjusted prevalence ratio [aPR], 1.04; 95% CI, 1.00–1.08; p = 0.043). Albeit not statistically significant, primary-only (aPR, 1.01; 95% CI, 0.97–1.06; p = 0.547) or secondary-only (aPR, 1.03; 95% CI, 0.98–1.08; p = 0.224) partnership types were positively associated with viral suppression. Partner support and strain were not associated with viral suppression in any partnership group. Being older and non-Hispanic Black were positively and negatively associated with viral suppression, respectively. Encouraging partnerships should be considered one of clinicians’ many tools to help middle-aged and aging MSM achieve long-term viral suppression.
Databáze: OpenAIRE
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