Supplementary Data from Circulating Tumor DNA Sequencing Analysis of Gastroesophageal Adenocarcinoma

Autor: Daniel V.T. Catenacci, Jeeyun Lee, Seung Tae Kim, Richard B. Lanman, Rebecca J. Nagy, Lesli A. Kiedrowski, Julie Johnson, Stacie Landron, Smita S. Joshi, Kelly L. Moore, Sara Kochanny, Samantha Lomnicki, Leah M. Chase, Steven B. Maron
Rok vydání: 2023
DOI: 10.1158/1078-0432.22475397
Popis: Supplementary Legend and Figures Supplemental Figure S1. Relationship between tumor burden, number of alterations, and tumor mutation burden. Supplemental Figure S2. Number of detected genomic alterations by stage. Supplemental Figure S3. Relative frequency of common (>5%) non-synonymous alterations between various ctDNA-NGS and tissue-NGS cohorts amongst patients with detectable alterations. Supplemental Figure S4. Distribution of oncogenic copy number with and without "adjustment" for maxVAF. Supplemental Figure S5. Serial NGS of ctDNA and tissue highlight spatio-temporal heterogeneity in patients with RTK alterations treated with matched targeted therapies.
Databáze: OpenAIRE