Left Atrial Volumetric and Strain Analysis by Three-Dimensional Speckle-Tracking Echocardiography in Noncompaction Cardiomyopathy: Results from the MAGYAR-Path Study

Autor: Tamás Forster, Péter Domsik, Györgyike Ágnes Piros, Attila Nemes, Anita Kalapos
Rok vydání: 2016
Předmět:
Adult
Male
medicine.medical_specialty
Noncompaction cardiomyopathy
lcsh:Diseases of the circulatory (Cardiovascular) system
Left atrium
Echocardiography
Three-Dimensional
Speckle tracking echocardiography
030204 cardiovascular system & hematology
Doppler echocardiography
left atrium
03 medical and health sciences
Ventricular Dysfunction
Left
0302 clinical medicine
strain
Left atrial
Internal medicine
Image Interpretation
Computer-Assisted
medicine
Humans
three-dimensional
In patient
Aged
Medicine(all)
function
medicine.diagnostic_test
business.industry
Congenital cardiomyopathy
Middle Aged
medicine.disease
Echocardiography
Doppler
medicine.anatomical_structure
030228 respiratory system
lcsh:RC666-701
Echocardiography
Cardiology
Female
speckle-tracking
Cardiology and Cardiovascular Medicine
business
Cardiomyopathies
Zdroj: Hellenic Journal of Cardiology, Vol 57, Iss 1, Pp 23-29 (2016)
ISSN: 1109-9666
DOI: 10.1016/s1109-9666(16)30014-8
Popis: Introduction Noncompaction cardiomyopathy (NCCM) is a rare congenital cardiomyopathy characterised by a distinctive 2-layered appearance of the myocardium due to hypertrabecularisation and deep intertrabecular recesses. The present study was designed to assess left atrial (LA) volumes and volumetric and strain-based functional properties by three-dimensional speckle-tracking echocardiography (3DSTE) in NCCM. Methods The study included 12 consecutive NCCM patients. Their results were compared to 20 age- and sex-matched healthy controls. Complete two-dimensional Doppler echocardiography and 3DSTE were performed in all cases. Results Calculated LA maximum (76.5 ± 26.8 mL vs. 45.3 ± 15.1 mL, p=0.0002) and minimum (56.9 ± 27.3 mL vs. 25.3 ± 15.2 mL, p=0.0002) volumes and LA volume before atrial contraction (67.1 ± 28.2 mL vs. 35.7 ± 16.4 mL, p=0.0004) were significantly greater in NCCM patients. Total, active, and passive LA emptying fractions proved to be smaller in NCCM. Peak global radial (−9.3 ± 7.8% vs. −16.8 ± 10.2%, p=0.05), circumferential (12.8 ± 8.4% vs. 26.2 ± 9.2%, p=0.0003), longitudinal (12.8 ± 8.2% vs. 22.5 ± 8.5%, p=0.004), and area (26.7 ± 18.5% vs. 51.6 ± 20.3%, p=0.001) strains were significantly smaller in NCCM patients as compared to matched controls. Conclusions Significantly greater LA volumes and compromised LA functional properties could be demonstrated by 3DSTE in patients with NCCM.
Databáze: OpenAIRE
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