Ultrastructure of Developing Feline Nonciliated Bronchiolar Epithelial Cells
| Autor: | Robert W. Henry, Mohammed S. Al-Tikriti |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Cell Respiratory Mucosa Mitochondrion Biology Pathology and Forensic Medicine chemistry.chemical_compound Structural Biology medicine Animals Apical cytoplasm Bronchioles Glycogen Epithelial Cells Cell biology Microscopy Electron Terminal Bronchioles medicine.anatomical_structure chemistry Cytoplasm Ultrastructure Cats Female Nucleus |
| Zdroj: | Ultrastructural pathology. 39(4) |
| ISSN: | 1521-0758 |
| Popis: | The ultrastructure of the developing bronchiolar cell was studied in six age groups: prenatal (60 d post-conception); postnatal (1-, 7-, 14- and 21-day-old); and adult. Following intratracheal fixation, the lung tissue was processed for scanning and transmission electron microscopy. The lining of terminal bronchioles consists of cuboidal to columnar nonciliated bronchiolar cells (NBCs) and ciliated with or without microvilli. NBCs were recognized by indented centrally located nucleus. The apical surface extended beyond the surface of neighboring cells and was covered by minute microvilli, except in prenatal kittens. The NBCs of the adult were characterized by abundant mitochondria and glycogen inclusions. In prenatal kittens, the cytoplasm was filled with patches of alpha and beta form of glycogen. Postnatally, glycogen was reduced in quantity, became scattered throughout the cytoplasm and was predominantly of the beta form. Islands of cytoplasm, separated from the apical cytoplasm were observed in the lumen of adult bronchioles. This suggests an apocrine mode of secretion. The NBCs attain maturity by three weeks of age. |
| Databáze: | OpenAIRE |
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