Transient Creatine Kinase Elevation Followed by Hypocomplementemia in a Case of Rotavirus Myositis
| Autor: | Saeko Suzuki, Rie Noguchi, Ryoichi Onuma, Setsuko Kitaoka, Satoru Kumaki, Yo-hei Watanabe, Natsuko Kusaka, Yuka Rokugo |
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| Rok vydání: | 2016 |
| Předmět: |
biology
business.industry lcsh:RJ1-570 Serum albumin Case Report lcsh:Pediatrics General Medicine 030204 cardiovascular system & hematology medicine.disease medicine.disease_cause Complement system Pathogenesis 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Rotavirus Immunology biology.protein medicine Creatine kinase Antibody Complication business Myositis |
| Zdroj: | Case Reports in Pediatrics, Vol 2016 (2016) Case Reports in Pediatrics |
| ISSN: | 2090-6811 2090-6803 |
| DOI: | 10.1155/2016/3034170 |
| Popis: | We report an infant case of rotavirus myositis, a rare complication of rotavirus infection. Complement levels of the patient were normal when serum creatine kinase (CK) level was at its peak and then decreased when the CK level became normalized. In a previous case report of rotavirus myositis, transient decrease of serum albumin, immunoglobulin, and complement levels was reported. The authors speculated that intravascular complement activation was caused by rotavirus and resulted in the pathogenesis of myositis, although complement levels at onset were not measured by the authors. In this report, however, we demonstrate that the complement activation of our patient is a result of, rather than the cause of, skeletal muscle damage. |
| Databáze: | OpenAIRE |
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