Total synthesis of scutellarin-7-O-Glucuronide

Autor:	Li-Ping Wu, Qian Liu, Gang Fang, Guo-Hong Zhang, Ya-Bo Duan, Song Wu, Jian-Mei Cui
Rok vydání:	2005
Předmět:	Pharmacology chemistry.chemical_classification Chemistry Flavone derivatives Organic Chemistry Flavonoid Acetophenones Pharmaceutical Science Total synthesis General Medicine Uronic acid Asteraceae Flavones Analytical Chemistry chemistry.chemical_compound Complementary and alternative medicine Yield (chemistry) Drug Discovery Michael reaction Molecular Medicine Organic chemistry Hydrogenation Scutellarin-7-O-glucuronide
Zdroj:	Journal of Asian Natural Products Research. 7:655-660
ISSN:	1477-2213 1028-6020
Popis:	Scutellarin-7-O-glucuronide (1) has been synthesized from 2-hydroxyl-4,5,6-trimethoxyacetophenone through eight steps, including Michael addition, cyclization, hydrogenation, hydroxyl protection, deprotection, etc. The overall yield of 13% is much higher than that reported (0.6%) by L. Farkas, G. Mezey-Vàndor et al. in 1974.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c145de37fce0e67d2b82996b4a6a2b https://doi.org/10.1080/1028602032000169587 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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