Copper-Catalyzed Ring Expansion of Vinyl Aziridines under Mild Conditions
| Autor: | Jean-Marc Campagne, Renata Marcia de Figueiredo, Kim Spielmann, Eleonora Tosi |
|---|---|
| Přispěvatelé: | Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
heterocycles copper catalysis 010405 organic chemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry Organic Chemistry Salt (chemistry) 010402 general chemistry Ring (chemistry) 01 natural sciences ring-expansion pyrrolines vinyl aziridines 0104 chemical sciences chemistry Polymer chemistry Copper catalyzed |
| Zdroj: | SYNLETT SYNLETT, Georg Thieme Verlag, 2021, 32, pp.517-520. ⟨10.1055/s-0040-1706007⟩ |
| ISSN: | 0936-5214 1437-2096 |
| Popis: | Vinyl aziridines are versatile starting materials toward ring-expansion transformations. Such processes are widely used to give various medium or larger N-heterocycles of synthetic interest. This letter describes a copper-catalyzed ring expansion of vinyl aziridines to 3-pyrrolines by using a Cu(I) salt [(CuOTf)2·toluene or Cu(MeCN)4·PF6]. In particular, this transformation occurs under mild conditions (THF, rt). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|