Postoperative Hyperamylasaemia in Cardiac Surgery
| Autor: | Hannu Paajanen, Matti Tarkka, T Sisto, Aimo Harmoinen, Isto Nordback |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Urology Renal function Urine Diagnosis Differential Excretion chemistry.chemical_compound Metabolic Diseases Internal medicine Preoperative Care medicine Humans Postoperative Period Derivation Coronary Artery Bypass Aged Analysis of Variance Creatinine business.industry Middle Aged medicine.disease Cardiac surgery Isoenzymes Pancreatitis chemistry Bypass surgery Amylases Linear Models Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Scandinavian Cardiovascular Journal. 31:137-140 |
| ISSN: | 1651-2006 1401-7431 |
| DOI: | 10.3109/14017439709058082 |
| Popis: | The mechanism of postoperative hyperamylasaemia was studied in 48 patients undergoing coronary artery bypass grafting (CABG). Mild hyperamylasaemia developed in 87% of the patients, and in 10% the serum amylase activity was > 1000 U/l. Serial measurements of serum salivary (S-) and pancreatic (P-) isoamylases indicated that hyperamylasaemia was highest 24 hours after CABG and consisted mainly of P-amylase component. Serum creatinine, creatinine clearance and urinary albumin concentration remained normal after CABG, excluding severe renal damage. The fractional clearance (i.e. relative to creatinine clearance) of P-amylase decreased more than of S-amylase (from 3.6 to 0.9% vs 1.3 to 0.8%). Decreased rate of excretion into urine, rather than pancreatic cellular damage, is the main source of hyperamylasaemia after CABG. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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