Effect of waterpipe tobacco smoke exposure on the development of metabolic syndrome in adult male rats

Autor: M.S. Awawdeh, Karem H. Alzoubi, Nour A. Al-Sawalha, Yehya Almahmmod, Omar F. Khabour
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Leptin
Physiology
Peptide Hormones
Social Sciences
Blood Pressure
030204 cardiovascular system & hematology
Tobacco
Waterpipe
Vascular Medicine
Biochemistry
Habits
0302 clinical medicine
Pregnancy
Immune Physiology
Medicine and Health Sciences
Smoking Habits
Medicine
Psychology
030212 general & internal medicine
Metabolic Syndrome
Innate Immune System
Multidisciplinary
medicine.diagnostic_test
Organic Compounds
Monosaccharides
Chemistry
Physiological Parameters
Prenatal Exposure Delayed Effects
Physical Sciences
Cytokines
Female
Adiponectin
Research Article
Science
Immunology
Carbohydrates
Smoking Water Pipes
03 medical and health sciences
Adipokines
Tobacco Smoking
Animals
Humans
Obesity
Smoke
Behavior
business.industry
fungi
Body Weight
Organic Chemistry
Chemical Compounds
Biology and Life Sciences
Molecular Development
medicine.disease
Hormones
Rats
body regions
Disease Models
Animal
Oxidative Stress
Blood pressure
Glucose
Hemostasis
Metabolic Disorders
Immune System
Metabolic syndrome
business
Lipid profile
Developmental Biology
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0234516 (2020)
ISSN: 1932-6203
Popis: The prevalence of metabolic syndrome is increased worldwide. Tobacco smoking increases the risk of developing metabolic syndrome. Waterpipe tobacco smoking has become a global trend of tobacco consumption and is as common as cigarette smoking. In this study, the effect of waterpipe tobacco smoke (WTS) on the development of metabolic syndrome in rats was evaluated. Adult Wistar rats were exposed for 19 weeks to either fresh air (control) or WTS for 1 hour daily/ 5 days per week (WTS). Central obesity, systolic blood pressure, lipid profile, glucose hemostasis and levels of leptin and adiponectin were evaluated. The WTS exposure increased body weight, abdominal circumference, systolic blood pressure and fasting glucose compared to control animals (P0.05). In conclusion, exposure to WTS has detrimental health effects leading to the development of metabolic syndrome in experimental animals.
Databáze: OpenAIRE
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