A case report of simultaneous medullary and papillary carcinoma of thyroid
| Autor: | Babak Peyro Shabany, Ali Sadrizadeh, Reza Ziaolhagh, Asma Ahrari Roudi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Proto-Oncogene Proteins B-raf endocrine system medicine.medical_specialty endocrine system diseases Medullary cavity Endocrinology Diabetes and Metabolism medicine.medical_treatment medullary thyroid cancer Diseases of the endocrine glands. Clinical endocrinology Papillary thyroid cancer Thyroid carcinoma 03 medical and health sciences 0302 clinical medicine Endocrinology hemic and lymphatic diseases medicine Humans papillary thyroid cancer Euthyroid Thyroid Neoplasms Lymph node braf mutations business.industry Thyroid Medullary thyroid cancer Neck dissection respiratory system Middle Aged RC648-665 medicine.disease 030104 developmental biology medicine.anatomical_structure Thyroid Cancer Papillary 030220 oncology & carcinogenesis Carcinoma Medullary Female Radiology business circulatory and respiratory physiology |
| Zdroj: | Endocrine Regulations, Vol 55, Iss 2, Pp 83-88 (2021) |
| ISSN: | 1336-0329 |
| Popis: | Objective. Medullary (MTC) and papillary (PTC) thyroid carcinoma are two different types of thyroid carcinoma with significant differences in origin. Their co-occurrence in a patient is a rare phenomenon. We report a patient with simultaneous presentation of both MTC and PTC. Case presentation. A 62-year-old euthyroid woman with a cervical mass was evaluated, underwent total thyroidectomy, and neck dissection. The examination revealed a MTC large nodule as well as a small nodule of the tall cell variant of PTC, along with the concomitant cervical lymph node metastases. Subsequently, the genetic analysis showed BRAF mutations. Adjuvant treatments including radioiodine and thyroid hormone replacement therapies were performed for the patient. Conclusions. The cooccurrence of MTC and PTC in the same patient is a rare phenomenon. The clinical manifestations and biological behavior of these cancers are completely different. Since the therapeutic strategy and prognosis are very different in these patients, accurate diagnosis of this coexistence is very important. |
| Databáze: | OpenAIRE |
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